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8.3. HEALTH AND FOOD SCIENCES
Bioanalytical instrument set for the molecular and cellular examination of candidate drugs
University of Debrecen, Faculty of Medicine
Project code: Project description:
GINOP-2.3.3.-15-2016-0020 • Research groups at the University of Debrecen, Faculty of Medicine (DE ÁOK)
do basic and applied research on cellular processes governing various diseases with
Project leader institution: the aim to provide up-to-date, useful knowledge to medical students who will be
University of Debrecen, Faculty able to readily use it in practice to improve medical treatments and patients’ quality
of Medicine of living. One of the priority R&D directions in the University of Debrecen focuses
on a wide range of proteins, particularly on their role in diseases and on their po-
Project leader: tential therapeutic use. The DE ÁOK has been operating high-quality core facilities
József Tőzsér organized into a network for more than a decade, providing access for both internal
and external research groups to the instruments, methodology and technical backg-
Project leader’s contacts: round that are essential for high quality research and competitive knowledge.
tozser@med.unideb.hu • The instruments procured in this project aim to extend the instrument park of the
Proteomics Core Facility (PCF, professional leader: József Tőzsér), the HTS Core
Amount of funding: Facility (HTCF, person in charge of instruments: Tamás Bíró), the Biomolecular
HUF 883,937,823 Interaction Core Facility (BICF, headed by Ferenc Erdődi) and the Molecular Cel-
lular Analytics Core Facility (MCACF, persons in charge of instruments: László
RI type: Distributed Csernoch and György Panyi) with instruments suitable for protein analytics and
the examination of protein-ligand interactions.
Website: https://kancellaria.pa- • Technical description/parameters of the research infrastructure:
lyazatok.unideb.hu/hu/node/74 • Transcend II TLX-1 Turboflow and Thermo Orbitrap Fusion Tribrid high-reso-
lution and high-precision LC-MS mass spectrometer with attachable nanoHPLC
and software with Computing server configuration
• Microscopic/electrophysiology system: LSM 880 microscope/electrophysiology
module
• Envision multiplate reader two detector dual emission system
• NanoTemper’s innovative microscale thermophoresis products for protein-protein
interaction research: Monolith NT.115Blue-Red, Monolith NT.LabelFree
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