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8.3. HEALTH AND FOOD SCIENCES
Establishment of a molecular biomarker research and service centre
Eötvös Loránd University, Centre for Higher Education and Industrial Cooperation in Biotechnology
Project code: Project description:
FIEK_16-1-2016-0005 Modern, personalized therapies are essentially built on molecular diagnostics, that
is, on the analysis of so-called molecular biomarkers. Molecular biomarkers are used
Project leader institution: to identify the best treatment for certain diseases or the monitoring of the efficacy
Eötvös Loránd University and safety of the treatment. Such analysis requires very extensive scientific knowledge
which is provided at a high level and capacity by Lágymányos Campus, ELTE and
Project leader: MTA TTK. The consortium created by ELTE, MTA TTK, Servier Research Insti-
Imre Kacskovics tute CCLS and CRU Hungary Ltd launched its program with the long-term goal
to lead domestic molecular biomarker research and to provide services in this area
Project leader’s contacts: for the clinical and pharmaceutical industry, the national healthcare system and cit-
imre.kacskovics@ttk.elte.hu izens.
Project partners: 12 research groups were established for the implementation of the research pro-
MTA TTK; CRU Kft.; Servier gramme, 7 of which work at ELTE TTK and 5 at MTA TTK in collaboration with
Kutatóintézet Zrt. CRU and Servier researchers and experts. One of the pillars of the project is to es-
tablish an accredited molecular biomarker laboratory and to purchase the research
Amount of funding: and diagnostic laboratory equipment needed for the implementation. The laboratory
HUF 2,558,627,617 will be located in a new building in the South Block of the ELTE Lágymányos Cam-
pus.
RI type: Single-site
Major R&D instruments of the research groups and the molecular biology and im-
Website: munobiology laboratory
https://fiek.elte.hu/
Fluoro ELISA Plate Reader, Plate shaker, flow cytofluorometry (HTS), PCR devices,
IVD gradient PCR machine, Veriti dx 96-well Thermal Cycler, fluorometer (Qubit
starter KIT), DNA and RNA preparation device, Agilent Bioanalyzer, high perfor-
mance chromatographic system, sterile laminar boxes, CO2 incubators, centrifuges,
inverted and fluorescence microscopes, freezers etc. The operation of the FIEK is
supported by a bioinformatics research group with an effectively managed, large data
storage capacity server (100 TB) that enables intensive bioinformatics data analysis
by many researchers (72 CPU cores, 768 GB RAM), with high-speed (10 G) net-
work and UPS.
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